In Indonesia, including Yogyakarta, breast cancer
occupies the majority of cases of cancer.
And approximately 20-35 percent of breast cancer in
Indonesia with HER2 positive type, so it has a tendency to grow more violent
and relatively younger patients (40-50 years).
It was raised from the principal investigator Dr.Johan Sardjito Kurnianda, SpPD-KHOM the launch of Global Security Research SafeHer Trastuzumab in Hotel Novotel Yogyakarta, Thursday (2/8).
Unlike in most of Europe and America over the process of
developing breast cancer and hormonal sufferers are elderly. Type of breast
cancer with HER2-positive breast cancer that develops is not through hormonal
processes, but because the HER2 protein is produced in excess.
"This type of breast cancer more quickly resistant
to standard radiation and chemotherapy drugs," said Johan.
Therefore, to cope with breast cancer with HER2-positive
status was given anti-HER2 (Trastuzumab) and the drug has proved effective as
monotherapy or in combination with standard chemotherapy. Because it can
increase the response to treatment, life expectancy and better quality of life
in patients with advanced breast cancer with HER2 positive.
According to Roche Health Medical Management, Dr. Arya
Wibitomo, during treatment with Trastuzumab is made through intravenous
infusion that takes 30-90 minutes.
Currently, research is being done SafeHer to make
innovations in the treatment of HER2 with Trastuzumab positive by injection
under the skin (subcutaneous).
'' With the injectable drug delivery is expected to be
more comfortable for patients, and safe because it only takes five minutes.
Expected later patients could inject themselves like giving insulin to patients
with diabetes mellitus,'' said Arya.
SafeHer study was conducted in 40 countries (300
hospitals) with 2,500 patients. In Indonesia, the study was started this year
in five hospitals of Education (Dr Dr Sardjito Yogyakarta, Jakarta
Ciptomangunkusumo RSUP, Dharmais Cancer Hospital, Jakarta, Bandung and RS Hasan
Sadikin Hospital Dr Sutomo Surabaya).
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